{"id":13407,"date":"2025-12-13T23:54:59","date_gmt":"2025-12-13T23:54:59","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=13407"},"modified":"2025-12-13T23:54:59","modified_gmt":"2025-12-13T23:54:59","slug":"chemical-investigation-of-active-constituents-in-leonotis-leonurus-lamiaceae-cultivated-in-iraq","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=13407","title":{"rendered":"Chemical Investigation of Active Constituents in Leonotis leonurus (Lamiaceae) Cultivated in Iraq"},"content":{"rendered":"

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The College of Pharmacy discussed a Master\u2019s thesis entitled “Chemical Investigation of Active Constituents in Leonotis leonurus<\/em> (Lamiaceae) Cultivated in Iraq” by the student Elaf Bassem Dawood, and the supervisor, Assistant Professor Doha Abdul Sahib Abdul Hussein Al-Shammaa, at the Pharmacognosy and Medicinal Plants Department.<\/span><\/p>\n

The study aimed to identify the active constituents of Leonotis leonurus<\/em> cultivated in Iraq, and to evaluate its potential as a natural source of bioactive compounds.<\/span><\/p>\n

The study included sequential extraction of Leonotis leonurus <\/em>using a Soxhlet apparatus and maceration, followed by identification of active compounds using various chromatographic techniques. Subsequently, structural elucidation was performed using infrared (FT-IR), ultraviolet (UV), and proton nuclear magnetic resonance (\u00b9H-NMR) spectroscopy techniques, in addition to derivatization methods.<\/span><\/p>\n

The results showed that Leonotis leonurus<\/em> is a promising and rich source of bioactive compounds, as chemical and spectroscopic analyses revealed a variety of active compounds with anticancer and anti-angiogenic properties. Furthermore, among the successfully isolated compounds were the coumarin scopoletin, the terpenoid lupeol, and the phytosterol \u03b2-sitosterol, all of which are known for their diverse therapeutic activities, including anti-inflammatory and antioxidant effects.<\/span><\/p>\n

The study recommended that additional advanced pharmacological and pharmacodynamic studies on Leonotis leonurus<\/em> should be conducted to further evaluate its therapeutic efficacy and explore its potential for future use in developing natural pharmaceutical preparations.<\/span><\/p>\n

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[vc_row][vc_column][vc_column_text] The College of Pharmacy discussed a Master\u2019s thesis entitled “Chemical Investigation of Active Constituents in Leonotis leonurus (Lamiaceae) Cultivated … <\/i>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":13410,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[7],"tags":[],"class_list":["post-13407","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-dissuasion"],"yoast_head":"\nChemical Investigation of Active Constituents in Leonotis leonurus (Lamiaceae) Cultivated in Iraq - College of Pharmacy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=13407\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Chemical Investigation of Active Constituents in Leonotis leonurus (Lamiaceae) Cultivated in Iraq - 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