{"id":14019,"date":"2026-01-14T21:13:08","date_gmt":"2026-01-14T21:13:08","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=14019"},"modified":"2026-01-14T21:13:08","modified_gmt":"2026-01-14T21:13:08","slug":"phytochemical-investigation-of-basella-alba-basellaceae-cultivated-in-iraq-and-assessment-of-its-antileishmanial-activity","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=14019","title":{"rendered":"Phytochemical Investigation of Basella alba (Basellaceae) Cultivated in Iraq and Assessment of Its Antileishmanial Activity"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The College of Pharmacy discussed the MSc thesis entitled \u201cPhytochemical Investigation of <em>Basella alba<\/em> (Basellaceae) Cultivated in Iraq and Assessment of Its Antileishmanial Activity\u201d by the student Sara Hamid Hachim and the supervisor, Assistant Professor Dr. Nabaa Mohammed Ibrahim, at the Pharmacognosy and Medicinal Plant Department.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The study aimed to characterize the phytochemical constituents of Basella alba cultivated in Iraq and to evaluate the antileishmanial activity of the petroleum ether fraction.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The study included defatting of the plant material using n-hexane, followed by Soxhlet extraction and successive solvent fractionation based on polarity. Phytochemical characterization of the obtained fractions was performed using thin-layer chromatography (TLC), high-performance liquid chromatography (HPLC), liquid chromatography\u2013mass spectrometry (LC\u2013MS), gas chromatography\u2013mass spectrometry (GC\u2013MS), proton nuclear magnetic resonance (^1H NMR), and Fourier-transform infrared spectroscopy (FT-IR). The antileishmanial activity of the petroleum ether fraction was assessed using the MTT assay, with Pentostam serving as the positive control.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The results showed that phytochemical analysis confirmed the presence of alkaloids, lupeol, \u03b2-sitosterol, and a variety of phenolic and flavonoid compounds. In addition, the petroleum ether fraction demonstrated a significant, dose-dependent antileishmanial activity against Leishmania tropica, as evidenced by the MTT assay results.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The study recommended that Iraqi Basella alba represents a potential source of bioactive phytochemicals with antileishmanial activity, supporting its possible application in pharmaceutical and drug-development research.<\/span><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"cz_14897\" class=\"cz_grid_p cz_14897\"><div class=\"cz_grid cz_grid_1 clr cz_grid_c3 cz_grid_1_no_title cz_grid_1_mid tac\"><div class=\"cz_grid_item cz_grid_first\"><\/div><div class=\"cz_grid_item \"><div data-title=\"5399914999918038137\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038137.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038137-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"5399914999918038137\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038137-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038137-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><div class=\"cz_grid_item \"><div data-title=\"5399914999918038140\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038140.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038140-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"5399914999918038140\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038140-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038140-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><div class=\"cz_grid_item \"><div data-title=\"5399914999918038629\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038629.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038629-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"5399914999918038629\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038629-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2026\/01\/5399914999918038629-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] The College of Pharmacy discussed the MSc thesis entitled \u201cPhytochemical Investigation of Basella alba (Basellaceae) Cultivated in Iraq and &#8230; <a class=\"cz_readmore\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=14019\"><i class=\"fa czico-132-arrows-8\" aria-hidden=\"true\"><\/i><span>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":14021,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3,7],"tags":[],"class_list":["post-14019","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news","category-dissuasion"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - 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