{"id":1754,"date":"2023-02-09T11:20:00","date_gmt":"2023-02-09T11:20:00","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=1754"},"modified":"2023-02-09T11:20:00","modified_gmt":"2023-02-09T11:20:00","slug":"the-faculty-of-pharmacy-discusses-the-phytochemistry-and-anti-toxic-activity-of-cancer-cells-of-the-iraqi-cypress-plant","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=1754","title":{"rendered":"The Faculty of Pharmacy discusses the Phytochemistry and Anti-toxic Activity of Cancer Cells of the Iraqi Cypress Plant"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The Faculty of Pharmacy discussed the dissertation under the title ( Study of Phytochemistry and Assessment of Anti-toxic Activity of Cancer Cells of the Iraqi Cypress Plant) for the student Amani Amer Tawfiq in the pharmacognosy and medicinal plants department and her supervisor, Professor Dr. Shatha Hussein Ali.\u00a0The aims of this work are focused on isolation, identification, and qualitative and quantitative analysis after extraction of phytochemicals using two different methods (Ultrasound Assisted Extraction and Soxhlet) from <em>Cupressus sempervirens <\/em>grown in Iraq.\u00a0Furthermore, isolation and estimation of essential oils were performed by two different methods (steam distillation and hydrodistillation) and two different growth stages (ripe and unripe) for plant leaves and fruits, and analyzed by gas chromatography-mass. The cytotoxicity effect was assayed for the ethyl acetate and n- hexane fractions of leaves against human breast cancer cells using a colorimetric-MTT assay.\u00a0The results show the highest extract yield resulted from ultrasound-assisted extraction compared to Soxhlet. Furthermore, good percentage yields of essential oil were obtained approximately 0.73% from leaves and 0.54% from ripe fruits.\u00a0Furthermore, with a concentration of 0.70%, the main component is amentoflavone.\u00a0\u00a0\u00a0\u00a0\u00a0 Hence, the cytotoxicity findings reveal good activity on human breast cancer cells with a half maximum inhibition concentration of about 6.66 \u00b5g\/ml for the ethyl acetate fraction, which has been related to the presence of several bioactive phenolic constituents such as biflavanoids. Finally, according to good findings, the Iraqi soil and environment may be suitable for this plant species.<\/span><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"cz_100771\" class=\"cz_grid_p cz_100771\"><div class=\"cz_grid cz_grid_1 clr cz_grid_c4 cz_grid_1_no_title cz_grid_1_mid tac cz_tooltip cz_grid_1_no_title\"><div class=\"cz_grid_item cz_grid_first\"><\/div><div class=\"cz_grid_item \"><div data-title=\"1\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/1.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/1-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"1\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/1-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/1-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><div class=\"cz_grid_item \"><div data-title=\"ce052623-6c98-4913-bddd-d119974754d1\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/ce052623-6c98-4913-bddd-d119974754d1.jpeg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/ce052623-6c98-4913-bddd-d119974754d1-600x600.jpeg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"ce052623-6c98-4913-bddd-d119974754d1\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/ce052623-6c98-4913-bddd-d119974754d1-600x600.jpeg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/02\/ce052623-6c98-4913-bddd-d119974754d1-150x150.jpeg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] The Faculty of Pharmacy discussed the dissertation under the title ( Study of Phytochemistry and Assessment of Anti-toxic Activity &#8230; <a class=\"cz_readmore\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=1754\"><i class=\"fa czico-132-arrows-8\" aria-hidden=\"true\"><\/i><span>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":1755,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3],"tags":[],"class_list":["post-1754","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - 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