{"id":3543,"date":"2023-07-05T07:18:33","date_gmt":"2023-07-05T07:18:33","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=3543"},"modified":"2023-07-05T07:18:33","modified_gmt":"2023-07-05T07:18:33","slug":"formulation-and-evaluation-of-baclofen-as-a-model-gastroretentive-solid-drug-delivery-system-using-the-fdm-3d-printing-technique","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=3543","title":{"rendered":"Formulation and Evaluation of Baclofen as a Model Gastroretentive Solid Drug Delivery System Using the FDM 3D Printing Technique"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The Faculty of Pharmacy discussed the PHD Degree thesis, entitled&#8221; Formulation and evaluation of baclofen as a model gastroretentive solid drug delivery system using FDM 3D printing technique &#8221; by <strong>Nuha Mohammed\u00a0 AbdulKhaleq <\/strong>and the supervisor,<strong> Prof. Dr. Mowafaq Mohammed Ghareeb <\/strong>in the Department of Pharmaceutics.This study aimed to sustain the release profile of BFN over 12 hours in the stomach by formulation of gastro-floating drug delivery dosage forms in two different approaches using hot melt extrusion (HME) and fused deposition modeling (FDM) 3D printing and then comparing between them and selecting the best approach, thereby decreasing the side effects of the drug and enhancing patient compliance.The thesis recommended Studying and comparing the bioavailability of BFN in both approaches and determining drug pharmacokinetics.<\/span><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"cz_107194\" class=\"cz_grid_p cz_107194\"><div class=\"cz_grid cz_grid_1 clr cz_grid_c2 cz_grid_l2 cz_grid_1_no_title cz_grid_1_mid tac cz_tooltip cz_grid_1_no_title\"><div class=\"cz_grid_item cz_grid_first\"><\/div><div class=\"cz_grid_item \"><div data-title=\"\u062a\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/07\/\u062a.png\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"500\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/07\/\u062a-1200x500.png\" class=\"attachment-codevz_1200_500\" alt=\"\" title=\"\u062a\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><div class=\"cz_grid_item \"><div data-title=\"\u0644\u0627\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/07\/\u0644\u0627.png\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"1200\" height=\"500\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/07\/\u0644\u0627-1200x500.png\" class=\"attachment-codevz_1200_500\" alt=\"\" title=\"\u0644\u0627\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] The Faculty of Pharmacy discussed the PHD Degree thesis, entitled&#8221; Formulation and evaluation of baclofen as a model gastroretentive &#8230; <a class=\"cz_readmore\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=3543\"><i class=\"fa czico-132-arrows-8\" aria-hidden=\"true\"><\/i><span>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":3544,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3,7],"tags":[],"class_list":["post-3543","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news","category-dissuasion"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - 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