{"id":4393,"date":"2023-12-08T13:34:26","date_gmt":"2023-12-08T13:34:26","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=4393"},"modified":"2023-12-09T13:59:08","modified_gmt":"2023-12-09T13:59:08","slug":"a-seminar-for-the-journal-club-on-the-new-tolfenamic-acid-derivatives-targeting-vegfr-synthesis-in-silico-studies-and-in-vitro-anticancer-assessment","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=4393","title":{"rendered":"A Seminar for The Journal Club on the New Tolfenamic Acid Derivatives Targeting VEGFR: Synthesis, in silico Studies, and in vitro Anticancer Assessment"},"content":{"rendered":"<div class=\"wpb-content-wrapper\"><p>[vc_row][vc_column][vc_column_text]<\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">Under the supervision of the Dean of the College of Pharmacy, Assistant Professor Dr. Sarmed H. Kathum Alkhateeb, the Scientific Affairs Unit in the College of Pharmacy\/University of Baghdad, held an in-person seminar entitled &#8220;New Tolfenamic Acid Derivatives with Hydrazine-1-Carbothioamide and 1,3,4-Oxadiazole Moieties Targeting VEGFR: Synthesis, in-silico Studies, and in vitro Anticancer Assessment,&#8221; which was delivered by Assistant Lecturer Worood Shihab Ahmed to present research published by the faculty members and postgraduate students in the Pharmaceutical Chemistry Department and to exchange ideas and access to the scientific productions.\u00a0The study aimed to prepare and conduct laboratory diagnosis for new compounds using spectroscopic analysis techniques such as IR spectroscopy, proton NMR, and precise elemental analysis. Additionally, a study on the molecular interaction of the prepared compounds with the epidermal growth factor receptor kinase (EGFR kinase) was done.\u00a0An experiment measuring the proliferation index of treated cells with compounds derived from tolfenamic acid was conducted using the MTT assay. This assay helps determine whether the prepared compound possesses biological activity that enables it to kill cancer cells.<\/span><\/p>\n<p>[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]<div id=\"cz_67002\" class=\"cz_grid_p cz_67002\"><div class=\"cz_grid cz_grid_1 clr cz_grid_c2 cz_grid_1_no_title cz_grid_1_mid tac cz_tooltip cz_grid_1_no_title\"><div class=\"cz_grid_item cz_grid_first\"><\/div><div class=\"cz_grid_item \"><div data-title=\"1\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/1-1.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/1-1-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"1\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/1-1-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/1-1-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><div class=\"cz_grid_item \"><div data-title=\"2\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/2-1.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/2-1-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"2\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/2-1-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/2-1-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><div class=\"cz_grid_item \"><div data-title=\"3\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/3-1.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/3-1-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"3\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/3-1-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/3-1-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><div class=\"cz_grid_item \"><div data-title=\"4\"><a class=\"cz_grid_link \" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/4-1.jpg\" data-xtra-lightbox><img loading=\"lazy\" decoding=\"async\" width=\"600\" height=\"600\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/4-1-600x600.jpg\" class=\"attachment-codevz_600_600\" alt=\"\" title=\"4\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/4-1-600x600.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2023\/12\/4-1-150x150.jpg 150w\" sizes=\"auto, (max-width: 600px) 100vw, 600px\" \/><div class=\"cz_grid_details\"><i class=\"fa fa-search cz_grid_icon\"><\/i><\/div><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"<p>[vc_row][vc_column][vc_column_text] Under the supervision of the Dean of the College of Pharmacy, Assistant Professor Dr. Sarmed H. Kathum Alkhateeb, the &#8230; <a class=\"cz_readmore\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=4393\"><i class=\"fa czico-132-arrows-8\" aria-hidden=\"true\"><\/i><span>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":4398,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3],"tags":[],"class_list":["post-4393","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v27.7 - https:\/\/yoast.com\/product\/yoast-seo-wordpress\/ -->\n<title>A Seminar for The Journal Club on the New Tolfenamic Acid Derivatives Targeting VEGFR: Synthesis, in silico Studies, and in vitro Anticancer Assessment - College of Pharmacy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=4393\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"A Seminar for The Journal Club on the New Tolfenamic Acid Derivatives Targeting VEGFR: Synthesis, in silico Studies, and in vitro Anticancer Assessment - College of Pharmacy\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text] Under the supervision of the Dean of the College of Pharmacy, Assistant Professor Dr. Sarmed H. 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