{"id":687,"date":"2022-09-30T22:17:46","date_gmt":"2022-09-30T22:17:46","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687"},"modified":"2022-09-30T22:17:46","modified_gmt":"2022-09-30T22:17:46","slug":"the-faculty-of-pharmacy-discussed-phytochemical-investigation-of-leucaena-leucocephala-family-leguminosae-cultivated-in-iraq-and-evaluation-of-its-anti-inflammatory-activity-in-rat-models","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687","title":{"rendered":"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The Faculty of Pharmacy discussed the master\u2019s thesis tagged \u201cPhytochemical Investigation of <em>Leucaena leucocephala<\/em> (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in Rats models\u201d for student Azal Satar Al-Baaj and her supervisor Lecturer. Dr. Thukaa Zuhair Abdul-Jalil in the Pharmacognosy and Medicinal Plants Department.\u00a0This study aimed to extract and investigate the phytochemicals that are present in the leaves and stems of <em>Leucaena leucocephala<\/em>, then isolate them and study their pharmacological effectiveness as an anti-inflammatory using plant extracts and compare them with the drug diclofenac sodium.\u00a0The study involved extracting two parts of the plant (leaves and stems) that had never been studied before using two different methods. The crude extracts were collected and dried before being subjected to preliminary analyses that included phytochemical tests, thin layer chromatography (TLC), gas chromatography\/mass spectrometry (GC\/MS), and high-performance liquid chromatography (HPLC).\u00a0\u00a0Many of the active compounds from these parts were isolated by HPLC and PLC, and then the isolated compounds were identified and characterized by thin layer chromatography (TLC), Fourier transformation of infrared spectra (FTIR), melting point, and ultraviolet-visible spectrophotometry.\u00a0The result proved the presence of phytochemical compounds (Lupeol, campesterol, stigmasterol, resveratrol, apigenin, rutin, quercetin, caffeine acid, p-coumaric acid, isorhamnetin, luteolin) that were identified, isolated, and purified.\u00a0The results of the anti-inflammatory activity study were good in ethyl acetate and n-butanol extracted from the leaves by the cold method. At a concentration of 250 mg\/kg, Iraqi Leucaena leucocephala demonstrated anti-inflammatory activity by reducing inflammation in Albino rat models by lowering serum TNF- and IL-6 levels, as well as the percentage of exudate and granuloma.\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-688 size-large\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1-1024x768.jpg\" alt=\"\" width=\"1024\" height=\"768\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1-1024x768.jpg 1024w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1-300x225.jpg 300w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1-768x576.jpg 768w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1-600x450.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Faculty of Pharmacy discussed the master\u2019s thesis tagged \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and &#8230; <a class=\"cz_readmore\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\"><i class=\"fa czico-132-arrows-8\" aria-hidden=\"true\"><\/i><span>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":688,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3,7],"tags":[],"class_list":["post-687","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news","category-dissuasion"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models - College of Pharmacy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models - College of Pharmacy\" \/>\n<meta property=\"og:description\" content=\"The Faculty of Pharmacy discussed the master\u2019s thesis tagged \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and ... more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\" \/>\n<meta property=\"og:site_name\" content=\"College of Pharmacy\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/collegeofpharmacy1\" \/>\n<meta property=\"article:published_time\" content=\"2022-09-30T22:17:46+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"960\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"copharm\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"copharm\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"1 minute\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#article\",\"isPartOf\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\"},\"author\":{\"name\":\"copharm\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83\"},\"headline\":\"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models\",\"datePublished\":\"2022-09-30T22:17:46+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\"},\"wordCount\":292,\"publisher\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization\"},\"image\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage\"},\"thumbnailUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg\",\"articleSection\":[\"Activates\",\"dissuasion\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\",\"name\":\"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models - College of Pharmacy\",\"isPartOf\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage\"},\"image\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage\"},\"thumbnailUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg\",\"datePublished\":\"2022-09-30T22:17:46+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg\",\"contentUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg\",\"width\":1280,\"height\":960},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#website\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/\",\"name\":\"College of Pharmacy\",\"description\":\"University of baghdad\",\"publisher\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization\",\"name\":\"University of Baghdad\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png\",\"contentUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png\",\"width\":200,\"height\":188,\"caption\":\"University of Baghdad\"},\"image\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/collegeofpharmacy1\",\"https:\/\/www.instagram.com\/college_of_pharmacy_uob\/?igsh=NWcwMnFpd2M5bDdt\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83\",\"name\":\"copharm\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g\",\"caption\":\"copharm\"},\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?author=9\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models - College of Pharmacy","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687","og_locale":"en_US","og_type":"article","og_title":"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models - College of Pharmacy","og_description":"The Faculty of Pharmacy discussed the master\u2019s thesis tagged \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and ... more","og_url":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687","og_site_name":"College of Pharmacy","article_publisher":"https:\/\/www.facebook.com\/collegeofpharmacy1","article_published_time":"2022-09-30T22:17:46+00:00","og_image":[{"width":1280,"height":960,"url":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg","type":"image\/jpeg"}],"author":"copharm","twitter_card":"summary_large_image","twitter_misc":{"Written by":"copharm","Est. reading time":"1 minute"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#article","isPartOf":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687"},"author":{"name":"copharm","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83"},"headline":"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models","datePublished":"2022-09-30T22:17:46+00:00","mainEntityOfPage":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687"},"wordCount":292,"publisher":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization"},"image":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage"},"thumbnailUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg","articleSection":["Activates","dissuasion"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687","name":"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models - College of Pharmacy","isPartOf":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#website"},"primaryImageOfPage":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage"},"image":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage"},"thumbnailUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg","datePublished":"2022-09-30T22:17:46+00:00","breadcrumb":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#primaryimage","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg","contentUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/09\/5-1.jpg","width":1280,"height":960},{"@type":"BreadcrumbList","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=687#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/en.copharm.uobaghdad.edu.iq\/"},{"@type":"ListItem","position":2,"name":"The Faculty of Pharmacy discussed \u201cPhytochemical Investigation of Leucaena leucocephala (Family: Leguminosae) cultivated in Iraq and evaluation of its anti-inflammatory activity in rat models"}]},{"@type":"WebSite","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#website","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/","name":"College of Pharmacy","description":"University of baghdad","publisher":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/en.copharm.uobaghdad.edu.iq\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization","name":"University of Baghdad","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png","contentUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png","width":200,"height":188,"caption":"University of Baghdad"},"image":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/collegeofpharmacy1","https:\/\/www.instagram.com\/college_of_pharmacy_uob\/?igsh=NWcwMnFpd2M5bDdt"]},{"@type":"Person","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83","name":"copharm","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g","caption":"copharm"},"url":"https:\/\/en.copharm.uobaghdad.edu.iq\/?author=9"}]}},"modified_by":"copharm","_links":{"self":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/687","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=687"}],"version-history":[{"count":0,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/687\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/688"}],"wp:attachment":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=687"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=687"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=687"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}