{"id":6962,"date":"2024-08-12T22:49:58","date_gmt":"2024-08-12T22:49:58","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962"},"modified":"2024-08-12T22:49:58","modified_gmt":"2024-08-12T22:49:58","slug":"preparation-and-evaluation-of-lercanidipine-hydrochloride-nanosuspension-as-a-sublingual-fast-dissolving-film","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962","title":{"rendered":"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film"},"content":{"rendered":"

[vc_row][vc_column][vc_column_text]<\/p>\n

The College of Pharmacy discussed the MSc thesis entitled \u201cPreparation and Evaluation of Lercanidipine Hydrochloride Nanosuspension as a Sublingual Fast-Dissolving Film\u201d by the student Zahraa Alaa Abass and the supervisor, Assistant Prof. Dr. Fatima J. Jawad, at the Pharmaceutics Department. The study aimed to prepare and characterize lercanidipine HCl nanosuspension to enhance the solubility and release rate and then incorporate the Nanosuspension into a fast-dissolving sublingual film to achieve fast release and rapid onset of action and to improve patient compliance.\u00a0The results showed that lercanidipine HCl\u00a0 nanosuspension exhibited significant improvement in dissolution rate, as in vitro dissolution studies revealed faster drug release, achieving 100% within 20 minutes. The study recommended the importance of conducting a clinical trial to assess the in vivo bioavailability of sublingual fast-dissolving films that include lercanidipine HCl nanoparticles. Moreover, it is crucial to conduct a comprehensive stability assessment over the long term to comprehend how temperature and humidity affect these films. Furthermore, further research and evaluations are essential to grasp patients’ preferences and tolerance towards sublingual fast-dissolving films with lercanidipine HCl nanoparticles, particularly when compared to the presently accessible film-coated tablets of lercanidipine HCl.<\/span><\/p>\n

[\/vc_column_text][\/vc_column][\/vc_row][vc_row][vc_column]

<\/div>
\"\"
<\/i><\/div><\/a><\/div><\/div>
\"\"
<\/i><\/div><\/a><\/div><\/div>
\"\"
<\/i><\/div><\/a><\/div><\/div><\/div><\/div>[\/vc_column][\/vc_row]<\/p>\n<\/div>","protected":false},"excerpt":{"rendered":"

[vc_row][vc_column][vc_column_text] The College of Pharmacy discussed the MSc thesis entitled \u201cPreparation and Evaluation of Lercanidipine Hydrochloride Nanosuspension as a Sublingual … <\/i>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":6963,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3,7,5],"tags":[],"class_list":["post-6962","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news","category-dissuasion","category-last-news"],"yoast_head":"\nPreparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film - College of Pharmacy<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film - College of Pharmacy\" \/>\n<meta property=\"og:description\" content=\"[vc_row][vc_column][vc_column_text] The College of Pharmacy discussed the MSc thesis entitled \u201cPreparation and Evaluation of Lercanidipine Hydrochloride Nanosuspension as a Sublingual ... more\" \/>\n<meta property=\"og:url\" content=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962\" \/>\n<meta property=\"og:site_name\" content=\"College of Pharmacy\" \/>\n<meta property=\"article:publisher\" content=\"https:\/\/www.facebook.com\/collegeofpharmacy1\" \/>\n<meta property=\"article:published_time\" content=\"2024-08-12T22:49:58+00:00\" \/>\n<meta property=\"og:image\" content=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg\" \/>\n\t<meta property=\"og:image:width\" content=\"1280\" \/>\n\t<meta property=\"og:image:height\" content=\"720\" \/>\n\t<meta property=\"og:image:type\" content=\"image\/jpeg\" \/>\n<meta name=\"author\" content=\"copharm\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"copharm\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"Article\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#article\",\"isPartOf\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962\"},\"author\":{\"name\":\"copharm\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83\"},\"headline\":\"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film\",\"datePublished\":\"2024-08-12T22:49:58+00:00\",\"mainEntityOfPage\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962\"},\"wordCount\":230,\"publisher\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization\"},\"image\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage\"},\"thumbnailUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg\",\"articleSection\":[\"Activates\",\"dissuasion\",\"last news\"],\"inLanguage\":\"en-US\"},{\"@type\":\"WebPage\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962\",\"name\":\"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film - College of Pharmacy\",\"isPartOf\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#website\"},\"primaryImageOfPage\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage\"},\"image\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage\"},\"thumbnailUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg\",\"datePublished\":\"2024-08-12T22:49:58+00:00\",\"breadcrumb\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962\"]}]},{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg\",\"contentUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg\",\"width\":1280,\"height\":720},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#website\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/\",\"name\":\"College of Pharmacy\",\"description\":\"University of baghdad\",\"publisher\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization\"},\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?s={search_term_string}\"},\"query-input\":{\"@type\":\"PropertyValueSpecification\",\"valueRequired\":true,\"valueName\":\"search_term_string\"}}],\"inLanguage\":\"en-US\"},{\"@type\":\"Organization\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization\",\"name\":\"University of Baghdad\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/\",\"logo\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/\",\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png\",\"contentUrl\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png\",\"width\":200,\"height\":188,\"caption\":\"University of Baghdad\"},\"image\":{\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/\"},\"sameAs\":[\"https:\/\/www.facebook.com\/collegeofpharmacy1\",\"https:\/\/www.instagram.com\/college_of_pharmacy_uob\/?igsh=NWcwMnFpd2M5bDdt\"]},{\"@type\":\"Person\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83\",\"name\":\"copharm\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g\",\"caption\":\"copharm\"},\"url\":\"https:\/\/en.copharm.uobaghdad.edu.iq\/?author=9\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film - College of Pharmacy","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962","og_locale":"en_US","og_type":"article","og_title":"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film - College of Pharmacy","og_description":"[vc_row][vc_column][vc_column_text] The College of Pharmacy discussed the MSc thesis entitled \u201cPreparation and Evaluation of Lercanidipine Hydrochloride Nanosuspension as a Sublingual ... more","og_url":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962","og_site_name":"College of Pharmacy","article_publisher":"https:\/\/www.facebook.com\/collegeofpharmacy1","article_published_time":"2024-08-12T22:49:58+00:00","og_image":[{"width":1280,"height":720,"url":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg","type":"image\/jpeg"}],"author":"copharm","twitter_card":"summary_large_image","twitter_misc":{"Written by":"copharm","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"Article","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#article","isPartOf":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962"},"author":{"name":"copharm","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83"},"headline":"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film","datePublished":"2024-08-12T22:49:58+00:00","mainEntityOfPage":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962"},"wordCount":230,"publisher":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization"},"image":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage"},"thumbnailUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg","articleSection":["Activates","dissuasion","last news"],"inLanguage":"en-US"},{"@type":"WebPage","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962","name":"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film - College of Pharmacy","isPartOf":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#website"},"primaryImageOfPage":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage"},"image":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage"},"thumbnailUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg","datePublished":"2024-08-12T22:49:58+00:00","breadcrumb":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962"]}]},{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#primaryimage","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg","contentUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/08\/pic1-1.jpg","width":1280,"height":720},{"@type":"BreadcrumbList","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=6962#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/en.copharm.uobaghdad.edu.iq\/"},{"@type":"ListItem","position":2,"name":"Preparation and Evaluation of Lercanidipine Hydrochloride\u00a0 Nanosuspension as a Sublingual Fast-Dissolving Film"}]},{"@type":"WebSite","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#website","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/","name":"College of Pharmacy","description":"University of baghdad","publisher":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization"},"potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/en.copharm.uobaghdad.edu.iq\/?s={search_term_string}"},"query-input":{"@type":"PropertyValueSpecification","valueRequired":true,"valueName":"search_term_string"}}],"inLanguage":"en-US"},{"@type":"Organization","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#organization","name":"University of Baghdad","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/","logo":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/","url":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png","contentUrl":"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2024\/05\/pharmacy-logo.png","width":200,"height":188,"caption":"University of Baghdad"},"image":{"@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/logo\/image\/"},"sameAs":["https:\/\/www.facebook.com\/collegeofpharmacy1","https:\/\/www.instagram.com\/college_of_pharmacy_uob\/?igsh=NWcwMnFpd2M5bDdt"]},{"@type":"Person","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/85a43e42ae13b942c002c21c7772fd83","name":"copharm","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/en.copharm.uobaghdad.edu.iq\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/f92b31e3166ccc8eb8809e0d2fd33dc624d190730b3e36686c99ffdac172690b?s=96&d=mm&r=g","caption":"copharm"},"url":"https:\/\/en.copharm.uobaghdad.edu.iq\/?author=9"}]}},"modified_by":"copharm","_links":{"self":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/6962","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/users\/9"}],"replies":[{"embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=6962"}],"version-history":[{"count":0,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/posts\/6962\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=\/wp\/v2\/media\/6963"}],"wp:attachment":[{"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=6962"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Fcategories&post=6962"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/en.copharm.uobaghdad.edu.iq\/index.php?rest_route=%2Fwp%2Fv2%2Ftags&post=6962"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}