{"id":746,"date":"2022-10-06T19:19:03","date_gmt":"2022-10-06T19:19:03","guid":{"rendered":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=746"},"modified":"2022-10-06T19:19:03","modified_gmt":"2022-10-06T19:19:03","slug":"the-faculty-of-pharmacy-discussed-the-phytochemical-investigation-of-iraqi-cicer-arietinum-of-whole-plant-extract","status":"publish","type":"post","link":"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=746","title":{"rendered":"The Faculty of Pharmacy discussed the &#8220;Phytochemical Investigation of Iraqi Cicer arietinum of whole plant extract&#8221;"},"content":{"rendered":"<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The Faculty of Pharmacy discussed the master&#8217;s thesis entitled \u201cPhytochemical investigation of Iraqi <em>Cicer arietinum<\/em> of whole plant extract&#8221; by Rawnaq Jamal Madhloom in the Pharmacognosy and Medicinal Plants Department and her supervisor, Assist. Prof. Dr. Mohammed Kamil Hadi.<\/span><\/p>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">The thesis aimed to focus on phytochemical investigation of the Iraqi Cicer arietinum whole plant and the analysis of chemical constituents according to what the study included:<\/span><\/p>\n<ol style=\"text-align: justify;\">\n<li><span style=\"font-size: 19px;\">The dried sample (50 gm) was extracted in a Soxhlet extractor with 500 ml of 90% methanol and then fractionated using hexane, chloroform, ethyl acetate, and n-butanol in different polarities and fractionations of different active constituents from the plant.<\/span><\/li>\n<li><span style=\"font-size: 19px;\">The numerous active components in the Cicer arietinum fractions were identified in preliminary fashion using several chemical tests and gas chromatography\/mass spectrometry (GC\/MS). These identifications were supported by thin-layer chromatography (TLC) with various solvent systems and ultraviolet light at (254 and 365) nm and with high-performance liquid chromatography (HPLC), high-performance-thin-layer chromatography (HPTLC). Preparative-layer chromatography (PLC) and high-performance liquid chromatography were used to complete the isolation process (HPLC).<\/span><\/li>\n<li><span style=\"font-size: 19px;\">Preliminary chemical analysis of the extracted materials revealed the presence of steroids, terpenoids, flavonoids, tannins, and coumarins. The phytoconstituents in the hexane fraction were found using gas chromatography\/mass spectrometry (GC\/MS).<\/span><\/li>\n<\/ol>\n<p style=\"text-align: justify;\"><span style=\"font-size: 19px;\">Results from thin-layer chromatography (TLC) and high-performance liquid chromatography (HPLC) showed that the plant&#8217;s n-butanol fraction included rutin and catechine, while the hexane and chloroform fractions contained p-coumaric acid, caffeic acid, and gallic acid. From the complete plant of the Iraqi <em>Cicer arietinum<\/em>, six active components have been identified. Analytical TLC, analytical HPLC, Fourier-transform infrared spectroscopy (FTIR), ultraviolet (UV), and a high-performance compact mass spectrometer were used to determine the structure of the separated chemicals (CMS). It was determined that the separated substances were lupeol, p-coumaric acid, caffeic acid, gallic acid, rutin, and catechine.\u00a0<\/span><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-747 size-large\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/1-2-1024x768.jpg\" alt=\"\" width=\"1024\" height=\"768\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/1-2-1024x768.jpg 1024w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/1-2-300x225.jpg 300w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/1-2-768x576.jpg 768w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/1-2-1536x1152.jpg 1536w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/1-2-600x450.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/1-2.jpg 1600w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-748 size-large\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/2-1-1024x768.jpg\" alt=\"\" width=\"1024\" height=\"768\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/2-1-1024x768.jpg 1024w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/2-1-300x225.jpg 300w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/2-1-768x576.jpg 768w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/2-1-1536x1152.jpg 1536w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/2-1-600x450.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/2-1.jpg 1600w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-749 size-large\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/3-1-768x1024.jpg\" alt=\"\" width=\"768\" height=\"1024\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/3-1-768x1024.jpg 768w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/3-1-225x300.jpg 225w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/3-1-1152x1536.jpg 1152w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/3-1-600x800.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/3-1.jpg 1200w\" sizes=\"auto, (max-width: 768px) 100vw, 768px\" \/><img loading=\"lazy\" decoding=\"async\" class=\"aligncenter wp-image-750 size-large\" src=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/11-1024x768.jpg\" alt=\"\" width=\"1024\" height=\"768\" srcset=\"https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/11-1024x768.jpg 1024w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/11-300x225.jpg 300w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/11-768x576.jpg 768w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/11-600x450.jpg 600w, https:\/\/en.copharm.uobaghdad.edu.iq\/wp-content\/uploads\/sites\/80\/2022\/10\/11.jpg 1280w\" sizes=\"auto, (max-width: 1024px) 100vw, 1024px\" \/><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Faculty of Pharmacy discussed the master&#8217;s thesis entitled \u201cPhytochemical investigation of Iraqi Cicer arietinum of whole plant extract&#8221; by &#8230; <a class=\"cz_readmore\" href=\"https:\/\/en.copharm.uobaghdad.edu.iq\/?p=746\"><i class=\"fa czico-132-arrows-8\" aria-hidden=\"true\"><\/i><span>more<\/span><\/a><\/p>\n","protected":false},"author":9,"featured_media":750,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_lmt_disableupdate":"","_lmt_disable":"","footnotes":""},"categories":[3,7],"tags":[],"class_list":["post-746","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-latest-news","category-dissuasion"],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v25.8 - 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