The faculty of pharmacy discussed the Msc thesis tagged “The Role of Clinical Pharmacist in Reducing Drug Related Problems in Decompensated Liver cirrhosis patients” by Ameer A. khazal and his supervisor, Dr.Mohammed Y. Jamal, in the Clinical pharmacy Department. The objective of this study was to Patients with decompensated cirrhosis have typically been prescribed a combination of therapeutic and prophylactic medications. Polypharmacy increases the probability of medication errors and drug related problems. Clinical pharmacists are highly effective at identifying, resolving, and preventing clinically important drug-related problems in their patients’ care. The objectives of the study were the identification and classification of drug-related problems, as well as the discussion of these problems with health care providers (physicians, pharmacists, and nurses) and patients. Reduce their incidence as effectively as possible and educate all research participants on the significance of following their prescribed drug regimen. Method :A prospective, interventional, and clinical study for 80 hospitalized decompensated liver cirrhosis patients was conducted at Baghdad Teaching Hospital and lasted for four months from the first of December 2021, until the 31st of March 2022. The study involved two phases, the first was an observational one to identify drug related problems and classify them according to the Pharmaceutical Care Network Europe classification version 9.1, and the second was interventional one to increase the awareness of patients and health care providers about those problems and to propose a proper solution for each one. Result:The majority of drug-related problems were attributable to the Effect of drug treatment not optimal in 41.5%, Adverse drug events (possibly) were detected in 41.5 %, and untreated symptoms or indications in 17%. Causes were drug overdose in 30.2%, patients unintentionally using the drug in the wrong way in 22.6%, and unavailability of the prescribed drug in 13.2%. Omeprazole and lactulose were the most common medications causing problems. The healthcare providers and patients accepted and fully implemented 71.7% of pharmacist interventions, while they denied 15.1% of them.Conclusion :Significant numbers of Iraqi patients with decompensated liver cirrhosis have drug-related problems, and the use of proton pump inhibitors at too high a dose is accountable for a large number of these problems. Physicians and clinical pharmacists collaborated exceptionally well.