Under the supervision of the esteemed Dean of the College of Pharmacy, Associate Professor Dr. Sarmed H. Kathem Alkhateeb, the Scientific Affairs Unit in the College of Pharmacy/University of Baghdad, held an in-person scientific seminar entitled “Navigation the Olfactory Pathway: Advancement in Pharmaceutical Nose to Brain Delivery” delivered by Postgraduate Pharmacist Salam Shanta Taher, a faculty member at the Pharmaceutics Department. The lecture focuses on direct nose-to-brain drug delivery, a novel and advanced method of transporting therapeutics directly to the brain, bypassing the blood-brain barrier (BBB). This route leverages the anatomical connections between the nasal cavity and the brain, particularly through the olfactory and trigeminal nerves, to allow drugs to reach the central nervous system (CNS) more effectively. The lecture included several topics, and the key element of the lecture was the role of nanocarriers in enhancing this drug delivery process. Nanotechnology-based systems, such as nanoparticles, liposomes, and dendrimers, are employed to protect drugs, improve their absorption, and enable targeted delivery. Nanocarriers also provide advantages like controlled release of drugs, enhanced permeability through the nasal epithelium, and increased drug stability. The lecture also highlights the significance of nasal delivery devices in optimizing the drug delivery process. Devices such as nasal sprays and inhalers ensure precise drug dosing and efficient distribution within the nasal cavity. Advanced devices, like electronic atomizers and multidose systems, are designed to enhance patient compliance and improve the overall efficiency of nasal drug delivery.
