Under the supervision of the Dean of the College of Pharmacy, Professor Dr. Sarmed H. Kathem Alkhateeb, the Scientific Affairs Unit at the University of Baghdad/College of Pharmacy held an in-person seminar entitled “Ameliorative Effect of Different Doses of Carvone in a Mice Model of Glycerol-Induced Rhabdomyolysis and Acute Kidney Injury” delivered by Pharmacist Abeer Riyadh Abd-Ali, the PhD student at the Pharmacology and Toxicology Department. The seminar aimed to focus on investigating the potential protective effects of carvone on skeletal muscle damage associated with rhabdomyolysis and its subsequent impact on acute kidney inflammation. The seminar included several topics, including the dose-dependent effects of carvone on skeletal muscle inflammation and acute kidney inflammation, in addition to elucidating the underlying mechanisms responsible for carvone’s protective actions. Furthermore, the seminar highlighted the cellular mechanisms underlying carvone’s protective effects, including the suppression of oxidative stress and modulation of pro-inflammatory cytokine expression. Collectively, these insights support the prospective development of carvone as a supportive therapeutic candidate for future clinical applications. The seminar concluded that the importance of using carvone as a potential protective agent against skeletal muscle and renal inflammation. The findings demonstrated that carvone exhibits notable anti-inflammatory and antioxidant properties, contributing to the attenuation of tissue damage resulting from muscle degradation and kidney injury. A dose-dependent increase in efficacy was observed, suggesting that higher concentrations of carvone may enhance its therapeutic potential in conditions affecting muscular and renal systems. These conclusions were substantiated by laboratory data and histopathological evaluations.
